Overview of Chosen Chemical Compounds and Intermediates

Overview of Chosen Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: That is an impurity linked to bortezomib, a proteasome inhibitor Utilized in the treatment method of numerous myeloma. Its synthesis or study is important for making certain the purity and basic safety in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor while in the synthesis of abiraterone acetate, a drug Employed in the treatment method of prostate most cancers by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-ten-1): A key compound while in the synthesis of imatinib, a drug that targets particular kinds of cancer, together with Long-term myelogenous leukemia (CML).
Docetaxel Intermediate: A compound used in the synthesis of docetaxel, a chemotherapy medication that treats different cancers which include breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are generally intermediates in the synthesis of gemcitabine, an anti-cancer drug. Their research is crucial for optimizing the manufacturing approach and making certain significant purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-5): Lapatinib is utilized to deal with breast most cancers, and these intermediates are associated with its creation.
Fulvestrant Intermediates: Fulvestrant is really an estrogen receptor antagonist Utilized in the remedy of breast cancer. Numerous intermediates assist in the synthesis of this drug.
Paclitaxel Facet Chain Acid (CAS NO. 949023-16-9): This intermediate is Employed in the synthesis Abiraterone of paclitaxel, a chemotherapy drug powerful in managing cancers for instance ovarian, breast, and lung cancer.
3. Other Notable Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Utilized in the treatment method of colorectal cancer and modest mobile lung most cancers.
3-Amino-one-hydroxyadamantane (CAS 702-82-9): This compound is associated with the synthesis of adamantane derivatives, that have numerous applications, including antiviral Houses.
Vildagliptin Intermediates: Used in the creation of vildagliptin, an oral drug for form two diabetes that inhibits the enzyme DPP-4 to control blood sugar amounts.
4. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-48-1): This compound is associated with the synthesis of assorted gluconic acid derivatives, which might be Utilized in food stuff, pharmaceutical, and benzotriazol-1-yl-tetramethyluroniumtetrafluoroborate industrial apps.
Canagliflozin Intermediate two: A precursor within the synthesis of canagliflozin, a medication employed to control variety two diabetic issues by inhibiting sodium-glucose co-transporter two (SGLT2).